Why does PMDD happen?
While the exact reason for PMDD is yet to be discovered, studies have pointed to certain potential causes.
A recent research conducted by the National Institute of Health (NIH) found that the cells from women suffering from PMDD react differently (and more sensitively) to fluctuations in reproductive hormone levels than in women without PMDD.
This heightened sensitivity affects the brain’s chemical and neurological pathways that regulate the mood and feeling of well-being, possibly leading to depression around period.
Since a woman’s reproductive hormone levels change from two weeks leading up to menstruation, this is the time period is when PMDD affected women experience their symptoms.