How does metformin help PCOS treatment?
PCOS is a hormonal disorder that commonly occurs in females of reproductive or childbearing age. It can cause prolonged or infrequent periods or raised levels of androgens (the male hormones). Small follicles or cysts (fluid-filled sacs) can develop in the ovaries, which prevents the regular release of eggs (ovulation).
One of the possible factors that may play a role in developing PCOS is an excess amount of insulin in the body. Insulin helps the cells of the body use glucose, or sugar. If the body cells become insulin resistant, blood glucose levels may rise, causing more insulin to be secreted.
Metformin works as a treatment for PCOS by enhancing the body’s sensitivity to insulin. This decreases the levels of circulating insulin and also produces a positive effect on adipose (fat) tissue.