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How to get pregnant with PCOS: Everything you need to know

If you’ve been diagnosed with PCOS, you might be wondering what that means for getting pregnant. Here, an expert answers all your conception-related PCOS questions.

How to get pregnant with PCOS

If you’ve been diagnosed with polycystic ovary syndrome (PCOS), one of the first things you might have heard about the condition is that it can make it harder to get pregnant. Although that can be true for some, it doesn’t make it impossible — far from it.

If you’re looking for advice on how to conceive with PCOS, you’ve come to the right place. From lifestyle changes to tried-and-tested fertility interventions, there are a range of ways you can boost your chances of getting pregnant. Let’s find out how with a little help from a professor of obstetrics, gynecology, and reproductive sciences.

Getting pregnant with PCOS: Why is it harder?

It’s true that for some people with PCOS, getting pregnant can take a little longer. That’s because PCOS — a common hormonal disorder that affects around one in ten women of reproductive age — can make some people ovulate irregularly, or not at all. As ovulation (the monthly release of an egg) is a vital part of getting pregnant, this irregularity can make things tricky — but more on that below.

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Scientists still aren’t exactly sure what causes PCOS, but they believe you’re more likely to develop it if it runs in your family or if you have insulin resistance.

While it’s named polycystic ovary syndrome, confusingly, you don’t always develop polycystic ovaries if you have PCOS. Instead, you may be diagnosed with PCOS if you have two of the following three symptoms:

  • Irregular or missed periods
  • A high level of “male” hormones, called androgens (which can cause excessive hair growth on the body and face, as well as acne and thinning of hair on the head)
  • Polycystic ovaries, which occur when small egg sacs on the ovaries become filled with fluid, known as cysts 

But back to how all this can affect your chances of getting pregnant. Lubna Pal, professor of obstetrics, gynecology, and reproductive sciences at Yale School of Medicine, explains that “in order for pregnancy to happen, you need to have an egg that is released from your ovaries [once a month].”

After ovulation, an unfertilized egg stays in the uterine tubes for 12 to 24 hours before it dissolves and is shed as part of a period. If it’s fertilized by sperm before then, however, it can lead to a successful pregnancy. But if you’re not having regular periods, it means you’re probably not ovulating regularly either. As a result, Pal explains, “the probability of conception goes down.” 

That’s not the only way PCOS may impact getting pregnant, however. One theory that’s been researched suggests that PCOS can cause hormonal imbalances that change the quality of your cervical fluid, making it harder for sperm to survive. 

Further research shows that being overweight may play a role in hormonal disorders like PCOS, which can in turn affect fertility. For example, being overweight is linked to anovulation (when an egg isn’t released during your menstrual cycle), menstrual disorders (such as heavy bleeding and painful cramps), and difficulties with assisted reproduction (like IVF). However, it’s important to note that not everyone who has PCOS is overweight, and many people who are overweight ovulate without a problem.

There’s also the link between infertility and stress to consider. PCOS and stress are known to be associated. One Iranian study, albeit a small one, found that just over 90% of women with PCOS displayed some level of stress. As Pal explains, stress along with a fluctuation in weight (both gain and loss) can alter the signaling of an important cycle-related hormone called the gonadotropin-releasing hormone (GnRH). “​​There are so many factors that can mess up the GnRH, which then translates into menstrual irregularity,” Pal says. “It’s like a 1,000-piece jigsaw puzzle.”

Despite the numerous ways PCOS can impact your ability to get pregnant, Pal advises that there are ways to try and work around it. “It’s about finding the right strategy that works for you,” she explains.

How much harder is it to get pregnant with PCOS? The statistics

We know that PCOS affects around one in ten women of reproductive age. Of these, 70% to 80% don’t always release an egg (ovulate) during their menstrual cycle, making conception impossible in these months. This might sound like a high figure, but it’s believed that most women with PCOS will eventually be able to get pregnant if they manage the condition with treatment.

One person who’s part of that statistic is Stephanie, 35, who says she has “always wanted to be a mum” for as long as she can remember. But following a checkup with her health care provider, after noticing a heavy and irregular cycle, stomach cramps, excessive hair growth, and weight gain, Stephanie was diagnosed with PCOS. A scan later found large cysts on her ovaries, and, insensitively, she was told it was “highly unlikely” she would conceive naturally.

How to get pregnant with PCOS

“It was gut wrenching,” she recalls. “I have always had a motherly instinct, so when you’re told that it may never happen, it sends you on a downward spiral.”

At the time, Stephanie was 27, weighed over 260 lb. (120 kg), and wasn’t actively trying to have a baby. But she still knew that one day she wanted to become a mother. After talking to her health care provider, she was placed on a contraceptive pill to help regulate her heavy and irregular cycle. She was also referred to a weight specialist, all of which eventually helped Stephanie to become pregnant when the time was right.

Is it possible to get pregnant with PCOS quickly?

When you decide you want to have a baby, it’s normal to feel like you want it to happen immediately. With a condition like PCOS, things can be a bit more complicated, but it is possible to get pregnant with PCOS quickly if you manage your health properly. Having said that, there’s no real metric for what “quick” is, apart from your own personal timeline, so try to keep that in mind if you decide you want to start trying.

“Probably 60% plus can achieve spontaneous ovulation through improved lifestyle and weight loss over a span of a few months,” says Pal. In that instance, provided you have one egg and your partner’s sperm is good quality, “success rates go back to what they are for an ovulatory woman [without PCOS].” 

This was the case for Stephanie, who is now a very proud mom to her two-and-a-half-year-old son. “When I did conceive, it was a complete and utter shock. It took four pregnancy tests and a scan to make me believe [I was pregnant],” she says.

Since managing her symptoms, Stephanie now has a more regular cycle and a lighter flow, and her ovarian cysts have shrunk. Increasing the amount of exercise she did, along with steady weight loss, also had some part to play. “I looked at it like a lifestyle choice,” she says. “I changed my eating habits, and they have continued to change. I do a lot of walking — I’m up to 10 km a day sometimes, and walking also helps mentally, as well as with weight loss.” 

At the time of her diagnosis, Stephanie recalls that she had “given up hope of having children.” But when the time was right for her to get pregnant, and with the help of a weight specialist, it was something that fortunately happened for her. “I can’t imagine life without my son now,” she says. 

We know weight loss isn’t always easy, especially if you have other factors at play, like hormonal imbalances. But the good news is that it doesn’t always require dramatic weight loss to make a difference. “All it takes is a loss of 5% of your excess weight” to improve the likelihood of getting pregnant, says Pal.

Of course, weight loss won’t be the necessary solution for everyone with PCOS who wants to have a baby. If lifestyle changes haven’t proven successful, or perhaps aren’t needed if you’re already active and maintain a balanced diet, a health care provider might recommend medication such as letrozole or clomiphene to help trigger ovulation. These oral pills are taken in short doses at the beginning of each menstrual cycle, usually for a number of cycles.

How to get pregnant with PCOS

If these options don’t work, intrauterine insemination (IUI), also known as artificial insemination, may be suggested to help you conceive. This is where sperm is inserted into the uterus in an attempt to cause fertilization. Alternatively, in vitro fertilization (IVF) is another fertility treatment your health care provider may suggest next, which involves your egg being fertilized in a lab and then transferred into your uterus. You can read more on how that works here.

Tips for getting pregnant with PCOS

As we’ve seen, there are various ways to try to get pregnant with PCOS, ranging from lifestyle changes to medical help. But there are some other things you can do to boost your chances of conceiving with PCOS, such as:

1. Track your menstrual cycle

Whether you have regular periods every month or more unpredictable, irregular bleeds, it’s always worth monitoring your cycle to better understand the way your body works better. A period-tracking app like Flo can help here, improving your chances of getting pregnant by predicting when you’re likely to be ovulating — even if you have an irregular cycle. Sign up here.

2. Give yourself the best possible chance

Wondering what’s the best age to get pregnant with PCOS? Generally speaking, for women under the age of 35, you have about a 25% chance of conceiving in the first month of trying and around an 85% chance in the first year. 

Fertility and age go hand in hand. As we age, fertility declines because of a decrease in egg count and in egg quality. Studies have shown that for women aged 35 to 39 years old, the chances of conceiving spontaneously are about half that of women aged 19 to 26 years. 

As we’ve seen, for those living with PCOS, getting pregnant can take a little bit longer, which is why it’s probably best not to delay the process if possible. “The longer you wait, the more emotional angst there is,” Pal explains. “This can cause more irregularity of periods. It becomes a catch-22.” 

That said, having a baby is a big decision, so it’s important that you feel ready. Having open conversations with your health care provider to find out all the information you need or reaching out to support services can make a huge difference.

3. Pay attention to the preconception phase

The preconception phase is defined as the three months before you conceive — and it’s more important than you might think. In fact, Pal says, “Ideally in utopia, we’d all be paying attention to the preconception phase.” 

Why? Well, a few lifestyle changes before actively trying can make all the difference to your chances, according to the Centers for Disease Control and Prevention. They recommend eating a healthy, balanced diet, drinking less alcohol, and exercising regularly to help prepare your body for getting pregnant. 

Taking 400 mcg of folic acid every day is a good idea too, as studies have shown this B vitamin to be “fundamental for growth, especially in the embryonic and fetal stages.”  Prenatal vitamins that include iron, calcium, and zinc are also advisable as these minerals are crucial to support pregnancy.” Some prenatal vitamins also contain folic acid, so we’d recommend speaking with your doctor first to make sure you’re not doubling up.

4. Optimize your vitamin D levels

Vitamin D may well play a part in your journey to becoming a parent, too. According to Pal, a deficiency in vitamin D has been linked with “ovulatory dysfunction,” which is the word given to abnormal, irregular, or absent ovulation. 

“Women with PCOS have a high prevalence of vitamin D deficiency,” says Pal, and science agrees. One study found around 67% to 85% of those living with PCOS to be vitamin D deficient. What scientists aren’t sure about just yet is whether or not you’re more likely to ovulate regularly with PCOS if you have sufficient levels of vitamin D. Regardless, the American College of Obstetricians and Gynecologists still recommends that vitamin D deficiency is treated while you’re trying to conceive and during pregnancy.

5. Get your partner checked

Pal says it’s easy to forget that “pregnancy is a team sport.” So don’t just assume PCOS is the reason it’s not happening for you. Schedule an appointment to get your partner’s sperm checked. As we’ve learned, in order for conception to happen naturally, an egg needs to be fertilized by a sperm. But if the sperm is not strong enough to meet the egg, or if your partner has a low sperm count, it “decreases the odds” that this will happen.

One-third of infertility cases are actually caused by male reproductive issues and could be related to issues including:

  • Low (or no) sperm production
  • Varicocele (which is an enlargement in the veins in the scrotum that results in a reduction of size and amount of sperm being produced) 
  • Imbalances in the “male” reproductive hormones (usually due to issues with hormone-producing glands)

How to get pregnant with PCOS: The takeaway

Remember: In many cases, having PCOS doesn’t mean you can’t start a family. Living with PCOS essentially means there are some factors that can make it harder to get pregnant. But, like with any health concern, it’s important to speak to your health care provider because everyone’s experience is different, and there are plenty of treatment options. 

“In some ways, PCOS is a label that acts as an alert to say, ‘Hey, be vigilant,’” Pal notes. “If infertility is your concern, use the information to maximize your well-being. Don’t be concerned about it. Just go and seek help because it’s easily, easily surmountable.”

One person who knows that to be true is mom-of-one Stephanie. Her key piece of advice? “Don’t give up hope,” she says. “Seek help and guidance from wherever possible, and don’t ignore it. I am so thankful and grateful for my little boy. It can happen for you; just don’t give up.”

Written by Rebecca Shepherd

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